Sterile pens and markers satisfy the regulatory need for control of writing instruments in the cleanroom. Sterile pens and markers eliminate the need to surface sanitize writing instruments for the cleanroom and allow the introduction of a single pack of pens and/or markers per shift. This greatly simplifies the tracking of cleanroom writing instruments. Available in many colors and styles, sterile pens and markers are sterilized in lots using ethylene oxide gas sterilization. They are supplied in any combination of pens and markers and can be single, double or triple packed. Each sterile pack includes a lot number for traceability.